TIGENIX (D)

Euronext Brussels announces that, from 22/03/2007, the common shares described below issued by TiGenix NV will be listed on Eurolist by Euronext:
- a maximum of 40 million EUR new ordinary shares, qualifying for dividend as from 01/01/2007, that are offered in public subscription as from 12 March 2007 up to and including 21 March 2007. These shares will be mentioned in the official price list under the name TiGenix NV with the mention WI until 27/03/2007 included (When Issued: cf infra).
- a maximum of 15% new shares following the over-allotment option, qualifying for dividend as from 01/01/2007.
- 14,157,017 existing ordinary shares of the company TiGenix NV, qualifying for dividend as from 01/01/2007.
- on a date to be specified later: a maximum of 1,226,084 to be issued shares from the exercice of warrants offered by TiGenix NV as part of a warrant plan.

Thresholds of listing: As provided in the ETA Nr 2004-433 dated 20/09/2002, the static price range will be set at +/-20% around the reference price. If the price is outside the static price range the stock will be reserved during 15 minutes. The new reference price used will be the treshold (up or down) reached previously. The static price range will be set at +/-10% of this new reference price. This procedure will be repeated until an opening price will be established. At the opening of the security, the opening price will be the new reference price with a static price range of +/-10% and a dynamic price range of +/-5%. Usual trading rules in term of thresholds and of reservation period will be applied.

When Issued: according to the terms of he offering described in the prospectus, investors have to be aware that the offered shares must be delivered on 27/03/2007. Euronext Brussels has indicated that it will cancel all transactions realized on the regulated market Eurolist by Euronext Brussels if the offered shares are not delivered on 27/03/2007. The attention of the public is drawn upon the fact that, from the first listing of the shares on the regulated market Eurolist by Euronext Brussels and until 27/03/2007, it has to take into account the eventuality as described above for every operation that it intends to realise through Euronext or over the counter.