Thorlabs Mini2P Imaging System Leverages poLight ASA TLens® for Optimal Neurological Imaging

07 Oct 2024 09:00 CEST

Imaging Workflow System on Display at Neuroscience 2024, Booth #1101

HORTEN, Norway - October 7, 2024 -- poLight
ASA (https://www.polight.com/home/default.aspx) (OSE: PLT) today announced that
Thorlabs (https://www.thorlabs.com/newgrouppage9.cfm?objectgroup_id=16296)'
Miniature Two-Photon Imaging System (Mini2P) features the TLens® Silver tunable
optics, delivering fast multiplane imaging with a <0.4ms response time in freely
moving specimens. Available in two MEMS scanner configurations, the lightweight,
head-mounted design allows for hundreds of neurons to be monitored in a single
field of view (FoV) with visualization of up to a thousand cells achievable
through X/Y/Z tunable calcium imaging. The Thorlabs Mini2P and complete Imaging
Workflow System is on display at the Society for Neuroscience
conference (https://www.sfn.org/meetings/neuroscience-2024) in booth #1101.

"We have made notable enhancements to the original Zong/Moser/Kavli
design (https://www.cell.com/cell/fulltext/S0092-8674(22)00197
-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS00928674
2
2001970%3Fshowall%3Dtrue), delivering improved imaging results at different
depths and orientations of in vivo neural activity," said Jeff Brooker, Life
Science CTO at Thorlabs VA Imaging Research. "Leveraging the low-power, fast
poLight TLens® electrotuneable lens, researchers can capture better z-scanning
data with reduced signal-to-noise ratios in low light settings. TLens® enables
fast and stable imaging of multiple interleaved planes, as well as 3D functional
imaging, providing critical insights that will advance neurological research."

"We continue to be amazed at the progress achieved with Mini2P technology," said
Dr. Oyvind Isaksen, CEO of poLight ASA. "Thorlabs imaging system enables
researchers to 'see' a new level of brain functionality, and we are pleased to
continue our fruitful collaboration."

Further information from:

Dr. Øyvind Isaksen, CEO, poLight ASA: +47 90 87 63 98

About poLight ASA

poLight ASA (OSE: PLT) offers a patented, proprietary tunable optics technology,
starting with its first product, TLens® which replicates "the human eye"
experience in autofocus cameras used in devices such as smartphones, wearables,
barcode scanners, machine vision systems and various medical equipment.
poLight's TLens® enables better system performance and new user experiences due
to benefits such as extremely fast focus, small footprint, no magnetic
interference, low power consumption and constant field of view. poLight is based
in Horten, Norway, with employees in Finland, France, UK, US, China, Taiwan, and
the Philippines. For more information, please visit https://www.polight.com

About Thorlabs

Thorlabs, a vertically integrated photonics products manufacturer, was founded
in 1989 to serve the laser and electro-optics research market. As that market
has spawned a multitude of technical innovations, Thorlabs has extended its core
competencies in an effort to play an ever-increasing role to serve the Photonics
Industry at the research end, as well as the industrial, life science, medical,
and defense segments. The organization's highly integrated and diverse
manufacturing assets include semiconductor fabrication of Fabry-Perot, DFB, and
VCSEL lasers; fiber towers for drawing both silica and fluoride glass optical
fibers; MBE/MOCVD epitaxial wafer growth reactors; extensive glass and metal
fabrication facilities; advanced thin film deposition capabilities; and
optomechanical and optoelectronic shops.

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